What is the prognosis for aggressive prostate cancer: Joe Biden announces he has prostate cancer that has spread to his bones

Prostate cancer uncovered: The story behind Joe Biden’s aggressive diagnosis and treatment choices.

Modified on:
May 19, 2025 10:00 am

Former President Joe Biden’s recent diagnosis with aggressive prostate cancer that has progressed to his bones has once more put the spotlight on this serious health illness. Biden is 82 years old, and what he’s facing isn’t just any prostate cancer. His doctors have reported a Gleason score of 9, which is on the very high end of the scale. That score tells us how aggressive the cancer cells look under a microscope. A score of 9 means the cells are abnormal and likely to grow and spread quickly. In short, this isn’t a slow-moving, sit-and-watch kind of cancer. It’s fast, and it’s strong.

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Implications and challenges 

What makes this even more challenging is that the cancer hasn’t stayed put—it has metastasized, meaning it’s moved beyond the prostate and into his bones. The propensity to affect areas like the spine, hips, and ribs is high. This is linked with much pain, loss of mobility, and the potential for fractures. The occurrence of bone metastases tends to indicate an advanced stage of cancer, impacting both treatment options and survival, although it’s not entirely without hope.

One thing working in Biden’s favor is that his cancer is hormone-sensitive. And that’s a big deal. It means the cancer still responds to treatments that block or lower male hormones, mainly testosterone, which fuels prostate cancer growth. That opens the door for a range of targeted treatments, from hormone therapy to newer, more advanced options. So yes, this is a serious diagnosis—no sugarcoating that. But it’s also not the end of the road. There are treatments, there’s research, and there’s still room for hope. And honestly, Biden’s openness about his condition might just help shine a light on the importance of early screening and conversations about men’s health, especially in older age.

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Prognosis and survival rates: what it means

Now let’s talk about something that’s probably on your mind. If you or someone you care about is facing this kind of diagnosis: 

  • What’s the prognosis? 
  • How much time might someone have?

When prostate cancer spreads to the bones, the outlook becomes more serious. But the truth is, there’s no one-size-fits-all answer. The prognosis depends on several things that go far beyond just the cancer itself.

For starters, doctors will look at the overall health of the patient. Is he relatively active and strong? Are there other medical conditions—like heart disease or diabetes—that could complicate treatment?

Someone who’s in good shape might handle aggressive therapies better and have more options on the table.

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Then there’s the extent of the cancer’s spread. If the cancer has reached just a few bone sites, that’s a different scenario than if it’s widespread throughout the skeleton. Doctors also consider how well the cancer is responding to treatment, especially hormone therapy. Some men respond quite well and can live for years with controlled disease, while others may have more resistant forms that progress faster.

So what do the numbers say?

You might come across studies that show 5-year survival rates ranging anywhere from 10% to 40% for men with advanced, metastatic prostate cancer. And yes, that range sounds wide—and maybe even a bit discouraging—but here’s the thing: those numbers are based on older data, and they’re just averages. They don’t take into account all the advancements we’ve made in recent years, and they certainly don’t reflect individual situations. Some people live well beyond those numbers.

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In fact, with today’s treatments—like next-generation hormone therapies, bone-targeted drugs, immunotherapies, and precision medicine—the landscape is changing. It’s no longer just about “how long”; it’s about how well someone can live with cancer. Many men with bone metastases are finding ways to manage symptoms, slow the disease, and maintain their independence for as long as possible.

The significance of early detection

Biden’s diagnosis points to the value of regular screening in detecting prostate cancer in early stages. Regular physical examinations and PSA tests can identify issues before they reach complicated stages. Early detection has the tendency to provide more effective therapies and results.

Despite the diagnosis of former President Biden being serious, the presence of various treatment options creates hope. Advances in medical care still improve the management of aggressive prostate cancer even in bone metastasis. Biden’s case is a reminder that checkups should be undertaken regularly and studies on cancer management should continue.

That said, it’s also important to be real about the challenges. This kind of cancer is still considered incurable at the metastatic stage, and treatment usually focuses on slowing progression, relieving symptoms, and improving quality of life. Some patients opt for more aggressive care, while others choose a more palliative route, prioritizing comfort over longevity. It’s deeply personal, and no two journeys look the same.

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Lawrence Udia
Lawrence Udiahttps://polifinus.com/author/lawrence-u/
I am a journalist specializing in delivering the latest news on politics, IRS updates, retail trends, SNAP payments, and Social Security. My role involves monitoring developments in these areas, analyzing their impact on everyday Americans, and ensuring readers are informed about significant changes that could affect their lives.

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